General

Meaning of opposing teeth for the election of the denture remains unclear

Defect studies, no reliable statements possible / IQWiG calls dentistry for more research

Whether the condition of the teeth in the opposite jaw part has an impact on the significance for patients benefit from fixed or removable dentures, remains an open question. Because appropriate studies are lacking, here no robust conclusions are possible at present. This is the result, the institute takes for Quality and Efficiency in Health Care (IQWiG) in its on 23. June 2009 published final report. The authors hold additional clinical comparisons for urgent and demanding the scientific dentistry, in particular to build up expertise in the actual trial. Not just a matter of appearance

Tooth gaps are not only an aesthetic problem. You may adversely affect the adjacent teeth and the teeth of the opposite jaw Also: problems with chewing, tooth decay, bruxism and migraine headaches are just some of the possible damages. Close can be the gaps by fixed prosthesis in the form of bridges or removable partial dentures. Both can also be set on implants.

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Adverse effects of the dietary supplement Hydroxycut

BVL refers to possible severe liver damage caused by the ingestion of the food supplement Hydroxycut

The Federal Office of Consumer Protection and Food Safety (BVL) points out that taking the food supplement Hydroxycut can cause severe liver damage. As a publication Finland can be seen, the product under the brand names "Iovate" and "Muscle Tech" is produced by the company Iovate Health Sciences in Oakville, Ontario. The products are sold by the company Iovate Health Sciences, Inc. USA. In Finland, the products through online shops offered and praised as items to increase fat burning.

If typical symptoms of liver damage are observed as loss of appetite, nausea, vomiting, abdominal pain, fatigue, dark urine or jaundice (jaundice), individuals should consult a doctor.

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Hormones accelerate joint wear

Obese hurt her hip and knee joints, not only by the extra pounds, the loads on it. According to recent studies also secreted from fatty tissue hormones contribute to the destruction of articular cartilage. If it is possible to explore these relationships further, could optimized therapies reduce the frequent joint degeneration, the German Society of Endocrinology (DGE).

Many people who need a new hip or an artificial knee joint are overweight. "According to a British study, a quarter of all joint replacement operations on the hip and two-thirds of the operations on the knee joint due to overweight and obesity in the population," says DGE Spokesman Professor Dr. Helmut Schatz, Bochum. It would seem, so at due to overuse of the joints due to the heavy weight. Recent studies show that hormones thereby also play a role.

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Active substance from green tea protects against HIV transmission from seed

Hamburg researchers discovered that an active ingredient from green tea, the infectivity of HIV-1 laboratory experiment reduces drastically. Ilona Hauber and colleagues from the Heinrich Pette Institute (HPI; www.hpi-hamburg.de) in Hamburg postulate that this inhibitor when it is in concentrated form in microbicidal vaginal cream, could protect against sexual transmission of HIV. The results of their study published virologists now in the renowned journal PNAS (online Early Edition 18. 2009 May).

Ulm scientists had detected 2 years ago, that in human semen finest threads, so-called amyloid fibrils, are included, which interact with HIV and the cell surface. This is done in the HIV intercalates in the protein network of fibrils, characterized closely reaches the cell surface and thus an effective infection of cells is made possible. The fibrils are called abbreviated SEVI (Semen-derived Enhancer of Viral Infection) and degradation products of a protein which is contained in high quantities in the seeds. With the help of SEVI to the infectivity of HIV increases dramatically. An inhibitor of SEVI degrades in seeds and render harmless, could thus also reduce the transmission of HIV during sexual transmission, as was the idea of ​​the Hamburg researchers.

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Diagnostic HIV: persistently high number

the Robert Koch Institute in total 2008 HIV diagnoses have been reported for the year 2.806. Opposite the 2007 year (2.774 diagnoses), this means no significant change. "The continuing high number shows that prevention and research are still important," says Jörg Hacker, President of the Robert Koch Institute. However, there are regional divergent developments. The new annual report with comprehensive data on HIV infections and AIDS-related illnesses has been published in the Epidemiological Bulletin 21 / 2009 and the RKI websites available (www.rki.de).

Detail of infection were for 85% of the year 2008 newly diagnosed HIV infections. Among these, men who have sex with men (MSM), with 65% remains the largest group. Here, the number of new diagnoses in 2008 over the previous year (2007) is virtually unchanged - 1.555 or 1.552 (in 2007 had among MSM still an increase of 12% over 2006 be registered).

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AIDS is not defeated - but prevention bears fruit

The new data from the representative survey "AIDS in Public Awareness 2008" by the Federal Center for Health Education (BZgA) show a further increase in protective behavior in the population. The condom sales figures in 2008 also reached a record level of 215 million units. Nevertheless, the fight against the spread of HIV in Germany must be continued with all vigor in order to consolidate the positive development and ideally further improve it

The new data from the survey sample "Public Awareness of AIDS 2008", with the Federal Centre for Health Education (BZgA) regularly examined knowledge, attitudes and behavior of the population in terms of HIV / AIDS as well as the range of educational activities, showing a further increase in protective behavior in the population.

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Outdoor work: get away with a whole skin

Now the sun lures people back into street cafes or at the lakes. But its warming rays has two faces. The stimulating and soothing effects of a tanning session runs quickly into the opposite, when the skin is exposed for too long to the sun. The subsequent sunburn she never forgets. Particularly at risk are two and a half million people in Germany, occupationally exposed frequently to suspend eight hours or longer the blazing summer sun. To them, the brochure is "light and shade - protection against solar radiation for workers outdoors", published by the Federal Institute for Occupational Safety and Health (BAuA).

In particular, workers in the construction industry, agriculture and forestry, however, are at risk from the summer sun in the service sector such as cleaners, chimney sweep or teachers. Finally, long-term, intensive influences their ultraviolet radiation components can lead to skin cancer.

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detect cancer before it develops

Forschungsverbund of TU München, Epigenomics AG and ASHIP Bavaria (KVB) is developing new ways of preventing

The Federal Ministry of Education and Research (BMBF) is funding a research project with a total volume of 1,3 million euros for colorectal cancer, which scientists of 2. Medical Clinic of the Klinikum rechts der Isar of the Technical University of Munich, the Bavarian Association of Statutory Health Insurance Physicians (KVB) and implement the company Epigenomics AG together. The aim of the project is to develop a new blood test that also precursors of colorectal cancer, called an adenoma and polyp can be detected. Compared to the usual colonoscopy this possibility for the patient would be much less complicated. A non-invasive blood test could thus contribute to complement existing prevention strategy significantly to reduce colorectal cancer mortality.

Colorectal cancer is approximately 73.000 new cases annually in Germany the most common gastrointestinal tumor and the cancer that is the second highest death toll calls in Europe and the US. The majority of cases are only discovered at an advanced stage, so that healing is often no longer possible. To improve the prognosis of this disease, nor would the cancer in the earliest possible stages, ideally in its precursor form (polyps), are detected. So could the patients in whom the cancer has not spread, be cured. At this stage, the chances of recovery are more than 90 percent. The removal of polyps also could be prevented in some cases even the outbreak of the disease. The introduction of colonoscopy at intervals of ten years as a screening procedure in 2002 should significantly improve the early detection of polyps and early stages of colorectal cancer. However, since currently the subject annually only 2,8 percent for eligible persons to this study, based on ten years of these are 28 percent, the success has been limited so far. A blood-based test that detects adenomas and early stages of colorectal cancer, would significantly improve the acceptance of colorectal cancer screening in the population. The endoscopic examination with the ability to simultaneously remove existing polyps, then especially those testing positive could be recommended.

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Asian martial arts increases pain thresholds

Study examines how Abhärtungstraining acts on pain sensation

In many Asian martial arts it belongs traditionally to the training, to inflict pain to be hardened permanently against pain. Scientists at the Department of Neurology of the University Hospital Münster have now investigated experimentally how this so-called Abhärtungstraining affects the pain sensation. In a pilot study, they surveyed to about 100 athletes in Germany, practicing martial arts.

"The majority said that would change both the intensity of pain and the affective evaluation of pain by Abhärtungsübungen. So reported many athletes that the pain still felt the practice of sport but is no longer impaired," said Prof . Dr. Dr. Stefan Evers, Vice-President of the German migraine and headache society (DMKG) and leader of the study. It could be that the activation of pain-inhibiting systems sustainable through infliction of pain also to positively influencing headaches.

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Art on finger fungus on fingers?

Artificial fingernails easily accommodate health risks

Artificial fingernails are trendy and for many women the finishing touch to summer outfit. But be careful with them the risk of allergies and fungal infections can increase significantly. Dr. Dieter Reinel, Dermatologist from Hamburg enlightens, and gives tips:

When attaching and curing acrylic nails steam are released. Possible consequences: contact allergies, blisters and itching, in particularly dramatic cases even numbness. Who is prone to allergies, should (often containing gel acrylic monomers and methacrylates) ask and pick up at his dermatologist advice in nail salon on the substances. There are now alternatives that reduce the risk.

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Go When intestinal bacteria surf

The bacterium Escherichia coli is part of the healthy human intestinal flora. But E. coli has also cause pathogenic relatives who diarrheal diseases: enterohämorraghische E.coli bacteria (EHECs). During an infection, they colonize the intestinal mucosa and cause as opposed to benign bacteria violations. The EHECs adhere tightly to the surface of mucosal cells and alter their affairs: One part of the cellular support skeleton - the actin skeleton - is so transformed that the cell surface forms among bacteria pedestal-growths, called pedestal. The bacteria are firmly anchored on these bases; the pedestal on the other hand are movable. Thus, the bacteria can surf on them sitting on the cell surface and reproduce it without being flushed from the intestine. But bring the bacterial host cell for remodeling of the actin cytoskeleton? Researchers at the Helmholtz Centre for Infection Research (HZI) have now elucidated the pathway, leading to the formation of this base.

"Prerequisite for this pathway is a special secretion system - a kind of molecular syringe through which to inject the bacteria all the proteins in the host cell," explains Theresia Stradal, head of the working group "Signalling and Motility" at the HZI. For the Pedestalbildung two factors, Tir and EspFU from the bacterium are introduced into the host cell. Then presents the host cell Tir on its surface; the bacterium recognizes "its" molecule Tir and adheres to the host cell. EspFU then triggers the signal for local actin conversion.

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